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Anhydro Abiraterone
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Documentation

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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

154229-20-6Anhydro Abiraterone

● Under Development

Catalogue No.:VL830016
CAS No.:154229-20-6
Mol. Formula:C24H29N
Mol. Weight:331.5 g/mol

Additional information on CAS 154229-20-6

Parent drug

Abiraterone

IUPAC Name

3-((8R, 9S, 10R, 13S, 14S)-10, 13-Dimethyl-2, 7, 8, 9, 10, 11, 12, 13, 14, 15-decahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine

Pharmacopoeial Synonyms

N/A

Other Synonyms

N/A

Smiles

C[C@@]12C(C3=CC=CN=C3)=CC[C@@]1([H])[C@]4([H])CC=C5C=CCC[C@]5(C)[C@@]4([H])CC2

InChI

InChI=1S/C24H29N/c1-23-13-4-3-7-18(23)8-9-19-21-11-10-20(17-6-5-15-25-16-17)24(21,2)14-12-22(19)23/h3,5-8,10,15-16,19,21-22H,4,9,11-14H2,1-2H3/t19-,21-,22-,23-,24+/m0/s1

Description

The compound Anhydro Abiraterone is a thoroughly characterized reference standard that complies with rigorous regulatory guidelines, including those from USP, EMA, JP, and BP. It is ideal for critical applications such as analytical method development, method validation (AMV), and quality control (QC), especially in the production of Abiraterone. Designed to support both Abbreviated New Drug Applications (ANDA) and New Drug Applications (NDA), this product delivers the precision required for reliable results. Additionally, it includes a detailed Structure Elucidation Report (SER), ensuring accuracy and dependability for advanced analytical purposes. Anhydro Abiraterone (CAS No: 154229-20-6) is an impurity formed during the synthesis of Abiraterone acetate which is a derivative of steroidal progesterone. It is classified as an adrenal inhibitor, used for hormonal therapy for advanced prostate and breast cancer.

References

Kavitapu, DasameswaraRao, et al. “New Stability Indicating RP-HPLC Method for the Determination of Abiraterone Acetate, Its Related Substances and Degradation Products in Bulk and Dosage Form.” Materials Today: Proceedings, vol. 34, 2021, pp. 469–78, https://doi.org/10.1016/j.matpr.2020.02.665. ?

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