Buspiron EP-Impurity C, auch als Buspiron-Bispyrimidinylpiperazinyl-Butan-Impurität bezeichnet, ist eine strukturell verwandte Verfahrensverunreinigung des anxiolytischen Piperazinderivats Buspiron. Die CAS-Nummer 257877-45-5 kennzeichnet die Verbindung mit der Summenformel C20H30N8 und einer Molmasse von 382,51 g/mol. Der Stoff entspricht einem überalkylierten oder durch Kettenhomologisierung entstandenen Nebenprodukt, das mit Synthese-, Kopplungs- oder Alkylierungswegen vereinbar ist und nicht primär einem oxidativen Abbau. Aufgrund des stark basischen, polyheteroaromatischen Gerüsts sind LC-MS/MS, hochauflösende LC-MS und gegebenenfalls NMR für die eindeutige Zuordnung erforderlich. Im regulatorischen Kontext wird sie als spezifizierte organische Verunreinigung bewertet.
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