Lagerstandorte

New Jersey, USA
Czech Republic, EU
Mumbai, India

* Vorbehaltlich Verfügbarkeit

Dokumentation

MSDS herunterladen

Beispiel-COA herunterladen

Enthält: HPLC, MASS/LC-MS, 1H-NMR, FT-IR, Gehalt, Structure Elucidation Report (SER) sowie zusätzliche analytische Daten je nach Produkt.

1809286-36-9Roxadustat Impurity 13

● Auf Lager

Katalog-Nr.::	VE0028100
CAS-Nr.::	1809286-36-9
Summenformel::	C19H17NO4
Molare Masse::	323.34 g/mol

Angebot anfordern

Zur RFQ-Liste hinzufügen

Zusätzliche Informationen zu CAS 1809286-36-9

Parent drug

Roxadustat

IUPAC-Name

Ethyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate

Pharmacopeial Synonyms

N/A

Synonyme

N/A

SMILES

O=C(OCC)C1=C(C2=C(C=C(C=C2)OC3=CC=CC=C3)C(C)=N1)O

InChI

InChI=1S/C19H17NO4/c1-3-23-19(22)17-18(21)15-10-9-14(11-16(15)12(2)20-17)24-13-7-5-4-6-8-13/h4-11,21H,3H2,1-2H3

Beschreibung

Roxadustat Impurity 13 (CAS 1809286-36-9) is a characterized synthetic byproduct detected in manufacturing and stability studies of Roxadustat, demanding precise analytical characterization and control. Structural elucidation by LC-MS, NMR and HRMS identifies its molecular features to inform degradation pathways and process optimization. Quantitative determination via validated HPLC methods supports impurity profiling, specification setting and batch release decisions, while forced degradation studies establish its formation kinetics and stability liabilities. Understanding this impurity is critical for impurity risk assessment, regulatory submissions and implementing corrective process controls to ensure consistent drug substance quality and compliance with ICH guidelines.