N,S-bis(Carboxymethyl)-L-cysteine, CAS 907565-13-3, is a sulfur-containing amino acid derivative with the molecular formula C7H11NO6S and molecular weight 237.23 g/mol. Structurally, it is a thioether/aminodicarboxylic acid adduct arising from carboxymethylation of both the amino and thiol functionalities of L-cysteine. Such species may form as a synthetic byproduct or during over-alkylation in cysteine-derived processes, and its polar, zwitterionic character favors reversed-phase retention challenges. Trace determination generally requires LC-MS/MS, sometimes coupled with ion-pair chromatography, because UV detection is limited. It is not a nitrosamine, but its presence may indicate process-related impurity formation requiring specification control.
References
Zeng, Z., Yang, D., Huang, X., & Xiao, Z. (2017). Effect of carbocisteine on patients with COPD: a systematic review and meta-analysis. International Journal of Chronic Obstructive Pulmonary Disease, Volume 12, 2277–2283. https://doi.org/10.2147/copd.s140603
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