Budesonide EP Impurity J, CAS 313474-59-8, is a brominated corticosteroid-related degradant or process impurity with formula C25H33BrO6 and molecular weight 509.43 g/mol. Structurally, it reflects modification of the budesonide scaffold at a halogenated carbon center, consistent with side products arising from electrophilic bromination or transformation of protected steroid intermediates. Its identity is typically resolved by LC-MS/MS with complementary high-resolution MS and orthogonal LC-UV or NMR confirmation, because closely related regioisomers may coelute. In pharmaceutical impurity profiling, such brominated species require careful control due to structural persistence and potential for misleading chromatographic interference.
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