It is a metabolite of Cyclophosphamide. Cyclophosphamide is evaluated in chemotherapy and is a part of the standard treatment of Cancer. It is activated to alkylating metabolites by cytochrome P-450.
References
« Gurtoo, H. L., et al. “Effects of the Induction of Hepatic Microsomal Metabolism on the Toxicity of Cyclophosphamide.†British Journal of Cancer, vol. 51, no. 1, Jan. 1985, pp. 67–75, https://doi.org/10.1038/bjc.1985.10.?Clarke, Lynn, and David J. Waxman. “Oxidative Metabolism of Cyclophosphamide: Identification of the Hepatic Monooxygenase Catalysts of Drug Activation.†Cancer Research, vol. 49, no. 9, American Association for Cancer Research, May 1989, pp. 2344–50, cancerres.aacrjournals.org/c
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