Apixaban Chloro Open Ring Impurity or ethyl 6-(4-(5-chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate, is a pyrazole derivative, it is a is an oral, direct, and highly selective factor Xa (FXa) inhibitor, pyrazole derivative and oral anticoagulant agent, antithrombin III to inhibit factor Xa.it is used for the treatment of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis.
References
Budovich, Aliaksandr, et al. Role of Apixaban (Eliquis) in the Treatment and Prevention of Thromboembolic Disease.” P & T : A Peer-Reviewed Journal for Formulary Management, vol. 38, no. 4, MediMedia USA, Inc., 2013, pp. 206–31, www.ncbi.nlm.nih.gov/pmc/articles/PMC3684191/.
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