Hyoscine Butylbromide EP Impurity G는 Hyoscine Apo-N-Butyl Impurity로도 불리는 구조적으로 정의된 트로판 알칼로이드 유도체로, 분자식은 C21H28NO3이며 분자량은 342.45 g/mol이다. 이는 합성 과정 또는 스트레스 조건에서 부틸화된 스코폴라민 골격에 작용하는 절단 또는 제거 반응으로부터 생성되는 탈4차화 또는 재배열성 분해 산물과 일치한다. 니트로사민이 아닌 불순물로서, 약전 기준에 따른 불순물 프로파일링과 규격 설정에서 규제학적 의미를 가진다. 검출은 일반적으로 동정 확인과 초미량 정량을 위한 LC-MS/MS를 필요로 하며, LC-HRMS와 직교적 크로마토그래피 분리가 피크 배정과 불순물 판별을 지원한다.
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