Ozanimod Alcohol Impurity, 즉 Des((2-hydroxyethyl)amino) 1-Hydroxy Ozanimod는 ozanimod의 공정 관련 또는 분해 관련 구조 유사체로서, hydroxyethylamino 치환기의 변형과 1-hydroxylated tricyclic pharmacophore의 보존을 특징으로 한다. 이 물질은 니트로사민은 아니지만, ICH Q3A에 따른 불순물 규명과 해당 시 ICH M7에 따른 독성학적 평가에서 중요하다. CAS 1201447-05-3, 분자식 C21H19N3O3, 분자량 361.39 g/mol이다. 미량 검출 및 정량에는 일반적으로 LC-MS/MS, 고분해능 LC-MS, 그리고 UV 검출을 동반한 직교 크로마토그래피 분리가 필요하다.
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