1,3-Adamantandiol (CAS 5001-18-3) ist ein bicyclisches, gesättigtes alicyclisches Diol, auch bezeichnet als 1,3-Dihydroxyadamantan oder Tricyclo[3.3.1.13,7]decan-1,3-diol. Mit der Summenformel C10H16O2 und einem Molekulargewicht von 168,23 g/mol handelt es sich um ein hydroxyliertes Adamantanderivat und nicht um eine reaktive elektrophile Verunreinigungsklasse. Es entsteht typischerweise durch unvollständige Funktionalisierung, Überoxidation oder als Nebenprodukt in adamantanbasierten Synthesen. Die Bestimmung erfordert gewöhnlich LC-MS/MS für Spurenprofile und GC-MS, häufig nach Derivatisierung, zur Bestätigung und Quantifizierung. Seine starre Struktur und geringe Polarität erschweren oft die chromatographische Trennung.
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