Buspirone EP Impurity N, auch als Buspirone Related Compound N bezeichnet, ist unter CAS 257877-44-4 registriert und besitzt die Summenformel C22H32N2O4 bei einer Molekülmasse von 388.50 g/mol. Strukturell handelt es sich um ein bis-spiroverknüpftes Diketondimer aus zwei buspironähnlichen Azaspiro[4.5]decan-Einheiten, die über eine Butandiyl-Brücke verbunden sind, und damit um eine prozessbedingte Verunreinigung. Seine Bildung ist plausibel als Folge von Kupplungs- oder Überalkylierungsreaktionen während der Herstellung des Spirogerüsts. Für die Charakterisierung werden üblicherweise LC-MS/MS, ergänzend LC-UV und gegebenenfalls NMR eingesetzt.
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