4-Descyano 4-Bromo Citadiol (CAS 488148-10-3) es una impureza estructuralmente relacionada presente en procesos de síntesis que requiere caracterización rigurosa para garantizar perfiles de calidad. Su identificación y cuantificación mediante HPLC | LC-MS y RMN permiten determinar su nivel residual y posibles rutas de formación. Esta sustancia presenta señales bromadas y ausencia del grupo cianuro | lo que condiciona su comportamiento cromatográfico y espectrométrico. Estudios de estabilidad y ensayos de degradación forzada ayudan a definir su persistencia y posibles productos secundarios. La documentación analítica detallada facilita la evaluación de riesgo y el establecimiento de límites aceptables en el control de calidad.
Referencias
“Escitalopram: MedlinePlus Drug Information.†Medlineplus.gov, 2022, medlineplus.gov/druginfo/meds/a603005.html#:~:text=Escitalopramisusedtotreat, monthsorlonger)inadults..
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