El 1,3-adamantanodiol (CAS 5001-18-3) es un diol alicíclico bicíclico saturado, descrito también como 1,3-dihidroxiadamantano o tricíclo[3.3.1.13,7]decano-1,3-diol. Con fórmula molecular C10H16O2 y peso molecular de 168,23 g/mol, corresponde a un derivado hidroxilado del adamantano y no a una clase de impureza electrófila reactiva. Suele asociarse con transformación funcional incompleta, sobreoxidación o formación de subproductos en rutas sintéticas basadas en adamantano. Su determinación normalmente requiere LC-MS/MS para el perfilado de trazas y GC-MS, a menudo con derivatización, para confirmación y cuantificación. La rigidez estructural y la baja polaridad pueden dificultar la resolución cromatográfica.
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