Acetaldehído (CAS 75-07-0; sinónimos: Acetic aldehyde | Ethyl aldehyde | Ethanal | Acetic ethanol) es una impureza volatile y reactiva que impacta la calidad y estabilidad de productos químicos y farmacéuticos; su presencia se asocia a oxidación | degradación y formación de acetales o paraldehído bajo condiciones ácidas o en presencia de catalizadores. Para control y cuantificación se emplean técnicas de cromatografía de gases con headspace o GC-MS | y métodos de derivatización con DNPH para HPLC; los límites habitualmente son sub-ppm a ppm según especificación. Recomendaciones para control incluyen almacenamiento refrigerado bajo atmósfera inerte | purga | destilación fraccionada y adsorbentes como carbón activado | además de monitorización periódica.
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