El bisfenol A, CAS 80-05-7, es un compuesto aromático difenólico con fórmula C15H16O2 y peso molecular de 228.29 g/mol. Se trata de un monómero industrial de gran volumen empleado en la fabricación de policarbonatos y resinas epoxi, y su presencia como impureza suele vincularse con material residual de síntesis, liberación hidrolítica desde matrices poliméricas o migración desde recubrimientos internos y plásticos de consumo. La evaluación regulatoria se centra en actividad endocrina, toxicidad reproductiva y persistencia ambiental, más que en su clasificación como impureza genotóxica según ICH M7. Su cuantificación requiere habitualmente LC-MS/MS o GC-MS, a menudo con derivatización e dilución isotópica.
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