2029205-64-7Apixaban Chloro Impurity

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Catalogue No.:	VL3170006
CAS No.:	2029205-64-7
Mol. Formula:	C24H22ClN5O3
Mol. Weight:	463.92 g/mol

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Additional information on CAS 2029205-64-7

Parent drug

Apixaban

IUPAC Name

1-(4-chlorophenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4, 5, 6, 7-tetrahydro-1H-pyrazolo[3, 4-c]pyridine-3-carboxamide

Pharmacopoeial Synonyms

N/A

Other Synonyms

p-Demethoxy p-Chloro Apixaban; 1H-Pyrazolo[3,4-c]pyridine-3-carboxamide, 1-(4-chlorophenyl)-4,5,6,7-tetrahydro-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-

Smiles

O=C(C1=NN(C2=CC=C(Cl)C=C2)C3=C1CCN(C4=CC=C(N5C(CCCC5)=O)C=C4)C3=O)N

InChI

InChI=1S/C24H22ClN5O3/c25-15-4-6-18(7-5-15)30-22-19(21(27-30)23(26)32)12-14-29(24(22)33)17-10-8-16(9-11-17)28-13-2-1-3-20(28)31/h4-11H,1-3,12-14H2,(H2,26,32)

Description

Apixaban Chloro Impurity (CAS No: 2029205-64-7) or 1-(4-chlorophenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide it is used to prevent serious blood clots from forming due to a certain irregular heartbeat by Inhibition of factor Xa leads to decreased conversion of factor II to IIa, resulting in decreased thrombin generation.

References

Hurst, Katherine, et al. “Quick Reference Guide to Apixaban.” Vascular Health and Risk Management, vol. Volume 13, July 2017, pp. 263–267, 10.2147/vhrm.s121944.