Dapagliflozin (C2,C3)-Epimer
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  • New Jersey, USA
  • Czech Republic, EU
  • Mumbai, India

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Dapagliflozin (C2,C3)-Epimer

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Catalogue No.:VE007775
CAS No.:N/A
Mol. Formula:C21H25ClO6
Mol. Weight:408.87 g/mol

Additional information on Dapagliflozin (C2 | C3)-Epimer

Parent drug

Dapagliflozin

IUPAC Name

(2R, 3S, 4R, 5S, 6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3, 4, 5-triol

Synonyms

N/A

Description

It is a metabolite of Dapagliflozin required for protein glycosylation. Dapagliflozin is a potent blocker of renal sodium-glucose cotransporter 2 that allows an insulin-independent method to better the type 2 diabetes hyperglycemia.

References

Raja, Mobeen, and Rolf K. H. Kinne. “Identification of Phlorizin Binding Domains in Sodium-Glucose Cotransporter Family: SGLT1 as a Unique Model System.†Biochimie, vol. 115, Aug. 2015, pp. 187–93, https://doi.org/10.1016/j.biochi.2015.06.003.?List, J. F., et al. “Sodium-Glucose Cotransport Inhibition with Dapagliflozin in Type 2 Diabetes.†Diabetes Care, vol. 32, no. 4, Dec. 2008, pp. 650–57, https://doi.org/10.2337/dc08-1863.?

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