Dapagliflozin Desethoxy Impurity
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1185339-44-9Dapagliflozin Desethoxy Impurity

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Catalogue No.:VL1650012
CAS No.:1185339-44-9
Mol. Formula:C19H21ClO5
Mol. Weight:364.82 g/mol

Additional information on CAS 1185339-44-9

Parent drug

Dapagliflozin

IUPAC Name

(2S, 3R, 4R, 5S, 6R)-2-(3-benzyl-4-chlorophenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3, 4, 5-triol

Pharmacopoeial Synonyms

N/A

Other Synonyms

N/A

Smiles

O[C@H]1[C@H](C2=CC=C(Cl)C(CC3=CC=CC=C3)=C2)O[C@H](CO)[C@@H](O)[C@@H]1O

Inchl

InChI=1S/C19H21ClO5/c20-14-7-6-12(9-13(14)8-11-4-2-1-3-5-11)19-18(24)17(23)16(22)15(10-21)25-19/h1-7,9,15-19,21-24H,8,10H2/t15-,16-,17+,18-,19+/m1/s1

Description

The compound Dapagliflozin Desethoxy Impurity is a highly characterized reference material that meets stringent regulatory standards, including those set by USP, EMA, JP, and BP. This product is essential for a variety of applications, such as analytical method development, method validation (AMV), and Quality Control (QC), particularly in the context of Dapagliflozin production. It is suitable for use in both Abbreviated New Drug Applications (ANDA) and New Drug Applications (NDA). Additionally, the product comes with a detailed Structure Elucidation Report (SER), ensuring its precision and reliability for comprehensive analytical use.

References

Kirillov, N. F., et al. “Synthesis of Substituted Methyl 5, 5-Polymethylene-2, 4-Dioxotetrahydropyran-3-Carboxylates.” Russian Journal of Organic Chemistry, vol. 46, no. 3, Mar. 2010, pp. 368–71, https://doi.org/10.1134/s1070428010030115.?

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