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1255529-28-2Edoxaban Impurity H
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| Catalogue No.: | VE008118 |
|---|---|
| CAS No.: | 1255529-28-2 |
| Mol. Formula: | C24H30ClN7O4S |
| Mol. Weight: | 548.06 g/mol |
Additional information on CAS 1255529-28-2
Parent drug
EdoxabanIUPAC Name
N-(5-Chloropyridin-2-yl)-N’-[(1S, 2S, 4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4, 5, 6, 7-tetrahydrothiazolo[5, 4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamidePharmacopoeial Synonyms
N/AOther Synonyms
Edoxaban (SSR)-Isomer; 2,4-diepi-EdoxabanSmiles
O=C(N[C@H]1C[C@@H](CC[C@@H]1NC(C(NC2=CC=C(C=N2)Cl)=O)=O)C(N(C)C)=O)C3=NC4=C(S3)CN(C)CC4InChI
InChI=1S/C24H30ClN7O4S/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34)/t13-,15+,17+/m1/s1Description
Edoxaban Impurity H is a well-characterized reference material that meets stringent regulatory standards set by USP, EMA, JP, and BP. It plays a key role in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial production of Edoxaban.
References
Cuker, Adam, and Holleh Husseinzadeh. “Laboratory Measurement of the Anticoagulant Activity of Edoxaban: A Systematic Review.†Journal of Thrombosis and Thrombolysis, vol. 39, no. 3, Feb. 2015, pp. 288–94, https://doi.org/10.1007/s11239-015-1185-7. ‌Camm, A. John, and Henri Bounameaux. “Edoxaban.†Drugs, vol. 71, no. 12, Aug. 2011, pp. 1503–26, https://doi.org/10.2165/11595540-000000000-00000.Request a Quote
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