Ezetimibe Desfluoro Chloro Impurity
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1700622-08-7Ezetimibe Desfluoro Chloro Impurity

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Catalogue No.:VE008752
CAS No.:1700622-08-7
Mol. Formula:C24H21ClFNO3
Mol. Weight:425.9 g/mol

Additional information on CAS 1700622-08-7

Parent drug

Ezetimibe

IUPAC Name

(3R, 4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

Pharmacopoeial Synonyms

N/A

Other Synonyms

Ezetimibe p-Chloro Aniline Analog

Smiles

O=C1N(C2=CC=C(Cl)C=C2)[C@H](C3=CC=C(O)C=C3)[C@H]1CC[C@@H](C4=CC=C(F)C=C4)O

InChI

InChI=1S/C24H21ClFNO3/c25-17-5-9-19(10-6-17)27-23(16-3-11-20(28)12-4-16)21(24(27)30)13-14-22(29)15-1-7-18(26)8-2-15/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1

Description

Ezetimibe Desfluoro Chloro Impurity is a well-characterized reference material that meets stringent regulatory standards set by USP, EMA, JP, and BP. It plays a key role in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial production of Ezetimibe. It is an impurity of Ezetimibe which is a type of medicine used to lower cholesterol. It is utilised to treat high blood cholesterol when high amount of a fatty substance called cholesterol in your blood is present.

References

NHS Choices. Ezetimibe. 2022, www.nhs.uk/medicines/ezetimibe/#:~:text=Ezetimibeisatypeof, calledcholesterolinyourblood..

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