L-Tyrosine, also designated Levodopa EP Impurity B and Phenylalanine EP Impurity C, is the aromatic amino acid 4-hydroxy-L-phenylalanine (CAS 60-18-4), molecular formula C9H11NO3, molecular weight 181.07 g/mol. It is structurally defined by a para-hydroxylated phenylalanine scaffold and is closely related biosynthetically and degradatively to catecholamine precursors. In pharmacopeial contexts, it may appear as a process-related impurity or as a constituent arising from incomplete conversion or hydrolytic/oxidative transformation in levodopa and phenylalanine manufacturing chains. Characterization commonly requires LC-MS/MS, LC-UV, and, where trace-level resolution is needed, HRMS or chiral LC methods.
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