727718-93-6Losartan Azide Impurity

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Catalogue No.:	VE006807
CAS No.:	727718-93-6
Mol. Formula:	C22H22ClN9
Mol. Weight:	447.93

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Additional information on CAS 727718-93-6

Parent drug

Losartan

IUPAC Name

5-(4′-((5-(azidomethyl)-2-butyl-4-chloro-1H-imidazol-1-yl)methyl)-[1,1′-biphenyl]-2-yl)-1H-tetrazole

Pharmacopoeial Synonyms

N/A

Other Synonyms

5-[2-[4-[[5-(azidomethyl)-2-butyl-4-chloroimidazol-1-yl]methyl]phenyl]phenyl]-2H-tetrazole; 1H-Tetrazole, 5-[4′-[[5-(azidomethyl)-2-butyl-4-chloro-1H-imidazol-1-yl]methyl][1,1′-biphenyl]-2-yl]- (9CI); 5-[4′-[[5-(Azidomethyl)-2-butyl-4-chloro-1H-imidazol-1-yl]methyl][1,1′-biphenyl]-2-yl]-2H-tetrazole

Smiles

CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CN=[N+]=[N-])Cl

InChI

InChI=1S/C22H22ClN9/c1-2-3-8-20-26-21(23)19(13-25-29-24)32(20)14-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-27-30-31-28-22/h4-7,9-12H,2-3,8,13-14H2,1H3,(H,27,28,30,31)

Description

Losartan Azide Impurity, also known 5-[2-[4-[[5-(azidomethyl)-2-butyl-4-chloroimidazol-1-yl]methyl]phenyl]phenyl]-2H-tetrazole is a highly characterized reference material. It fully complies with stringent regulatory standards, including those set by USP, EMA, JP, and BP. This product is essential for use in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial production of Losartan. Moreover, it comes with a detailed Structure Elucidation Report (SER), ensuring its accuracy and reliability for a wide range of analytical applications. It is the class of agents introduced to treat hypertension. This novel agent binds competitively and selectively to all subtype one receptors, thereby blocking All-induced physiological effects.