1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo [4,3-d]pyrimidine-5-yl)-4-ethoxy phenyl]sulfonyl]-piperazine

Status: In-stock

It is an impurity present in Sildenafil. Sildenafil is a phosphodiesterase inhibitor, sildenafil prevents the breakdown of cyclic guanosine monophosphate by inhibiting cGMP-specific phosphodiesterase type 5. The result of doing so allows cGMP to present in both the penis and pulmonary vasculature to elicit smooth muscle relaxation and vasodilation that relieve pulmonary arterial hypertension and increased the flow of blood into the spongy erectile tissue of the penis that consequently allows it to grow in size and become erect and rigid, which is used for the treatment of erectile dysfunction.

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Additional information on 1-[[3-(4 | 7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo [4 | 3-d]pyrimidine-5-yl)-4-ethoxy phenyl]sulfonyl]-piperazine

Catalogue No. VE009884
CAS No. N/A
Molecular Formula C21H28N6O4S
Molecular Weight 460.54 g/mol
Parent drug Sildenafil
IUPAC Name 1-[[3-(4, 7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo [4, 3-d]pyrimidine-5-yl)-4-ethoxy phenyl]sulfonyl]-piperazine
Synonyms N/A
References Konstantinos, & Hatzimouratidis. (2006). Sildenafil in the treatment of erectile dysfunction: an overview of the clinical evidence. Clinical Interventions in Aging, 1(4), 403–414. https://doi.org/10.2147/ciia.2006.1.4.403
Status In-stock

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1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo [4,3-d]pyrimidine-5-yl)-4-ethoxy phenyl]sulfonyl]-piperazine

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