1162-53-4: 16-Dehydropregnolone

16-Dehydropregnolone (CAS No: 1162-53-4) is an antihyperlipidemic agent used in controlling cholesterol homeostasis that acts by lowering serum lipids by regulating the key hepatic genes accountable for cholesterol metabolism.

Additional information

Catalogue No.

VE007839

CAS No.

1162-53-4

Molecular Formula

C21H30O2

Molecular Weight

314.46 g/mol

IUPAC Name

1-((3S, 8R, 9S, 10R, 13S, 14S)-3-hydroxy-10, 13-dimethyl-2, 3, 4, 7, 8, 9, 10, 11, 12, 13, 14, 15-dodecahydro-1Hcyclopenta[a]phenanthren-17-yl)ethanone

References

Ramakrishna, Rachumallu, et al. “16-Dehydropregnenolone Lowers Serum Cholesterol by Up-Regulation of CYP7A1 in Hyperlipidemic Male Hamsters.” The Journal of Steroid Biochemistry and Molecular Biology, vol. 168, Apr. 2017, pp. 110–17,  https://doi.org/10.1016/j.jsbmb.2017.02.013.

Status

In-stock