4’-Methylbiphenyl-2-carboxylic Acid
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Documentation

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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

7148-03-04’-Methylbiphenyl-2-carboxylic Acid

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Catalogue No.:VE009381
CAS No.:7148-03-0
Mol. Formula:C14H12O2
Mol. Weight:212.24 g/mol

Additional information on CAS 7148-03-0

Parent drug

Irbesartan

IUPAC Name

4′-Methyl-[1, 1′-biphenyl]-2-carboxylic Acid

Synonyms

N/A

Description

4’-Methylbiphenyl-2-carboxylic Acid(CAS No: 7148-03-0) or 4'-Methyl-[1,1'-biphenyl]-2-carboxylic Acid, is an angiotensin receptor blocker, that is used to treat hypertension or diabetic nephropathy, it prevents angiotensin II binding to the AT1 receptor in tissues. The volume of distribution is 53-93L and is 90% protein bound in plasma.

References

Burnier, Michel, et al. “Long-Term Use and Tolerability of Irbesartan for Control of Hypertension.” Integrated Blood Pressure Control, Apr. 2011, p. 17, https://doi.org/10.2147/ibpc.s12211. ‌

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