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1629778-77-3Abiratetone Succinate
● Under Development
| Catalogue No.: | VL830029 |
|---|---|
| CAS No.: | 1629778-77-3 |
| Mol. Formula: | C28H35NO4 |
| Mol. Weight: | 449.6 g/mol |
Additional information on CAS 1629778-77-3
Parent drug
AbirateroneIUPAC Name
4-(((3S, 8R, 9S, 10R, 13S, 14S)-10, 13-dimethyl-17-(pyridin-3-yl)-2, 3, 4, 7, 8, 9, 10, 11, 12, 13, 14, 15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-4-oxobutanoic acidPharmacopoeial Synonyms
N/AOther Synonyms
N/ASmiles
O=C(O)CCC(O[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)C(C5=CC=CN=C5)=CC[C@@]4([H])[C@]3([H])CC=C2C1)=OInChI
InChI=1S/C28H35NO4/c1-27-13-11-20(33-26(32)10-9-25(30)31)16-19(27)5-6-21-23-8-7-22(18-4-3-15-29-17-18)28(23,2)14-12-24(21)27/h3-5,7,15,17,20-21,23-24H,6,8-14,16H2,1-2H3,(H,30,31)/t20-,21-,23-,24-,27-,28+/m0/s1Description
Abiratetone Succinate or 4-(((3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-4-oxobutanoic acid, it is a decreases in PSA levels, tumor shrinkage and is inhibitor of the steroidal enzyme CYP17A1. it is used in the treatment of prostate cancer.References
Goldberg, Tamara, and Evangelina Berrios-Colon. “Abiraterone (Zytiga), a Novel Agent for the Management of Castration-Resistant Prostate Cancer.†Pharmacy and Therapeutics, vol. 38, no. 1, 1 Jan. 2013, pp. 23–26, www.ncbi.nlm.nih.gov/pmc/articles/PMC3628169/.Request a Quote
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