Abrocitinib Related Compound 3 Or (1s,3s)-N1-methyl-N1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)cyclobutane-1,3-diamine, Abrocitinib Related Compound 3 is an impurity present in Abrocitinib. Abrocitinib affects by blocking the signaling of pro-inflammatory cytokines, which are implicated in atopic dermatitis. Abrocitinib is a Janus kinase inhibitor, which is used for the treatment of atopic dermatitis.
References
Nezamololama, N., Fieldhouse, K., Metzger, K., & Gooderham, M. (2020). Emerging systemic JAK inhibitors in the treatment of atopic dermatitis: a review of abrocitinib, baricitinib, and upadacitinib. Drugs in Context, 9, 1–7. https://doi.org/10.7573/dic.2020-8-5
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