2490433-97-9: Acalabrutinib Impurity 11

Acalabrutinib Impurity 11 (CAS no.-2490433-97-9) IUPAC Name-(S)-4-(9-(1-(but-2-ynoyl)pyrrolidine-2-yl)-4-methyl-2-oxo-2H-imidazo[5′,1′:3,4]pyrazino[1,2-a]pyrimidin-11-yl)-N-(pyridine-2-yl)benzamide. Its an impurity of acalabrtinib. Acalabrutinib is a selective irreversible second-generation BTK inhibitor used against solid tumors.

Additional information

Catalogue No.

VE007042

CAS No.

2490433-97-9

Molecular Formula

C30H25N7O3

Molecular Weight

531.6 g/mol

IUPAC Name

(S)-4-(9-(1-(but-2-ynoyl)pyrrolidin-2-yl)-4-methyl-2-oxo-2H-imidazo[5', 1':3, 4]pyrazino[1, 2-a]pyrimidin-11-yl)-N-(pyridin-2-yl)benzamide

References

Wu, Jingjing, et al. “Acalabrutinib (ACP-196): A Selective Second-Generation BTK Inhibitor.” Journal of Hematology & Oncology, vol. 9, no. 1, Mar. 2016, https://doi.org/10.1186/s13045-016-0250-9.

Status

In-stock