2484719-11-9: Alpha-epoxyabiraterone acetate
Alpha-epoxyabiraterone acetate (CAS No: 2484719-11-9) is an intermediate of Abiraterone acetate which is a derivative of steroidal progesterone. It is utilized in the treatment of metastatic castration (mCRPC) and the treatment of metastatic high-risk castration-sensitive prostate cancer.
17-(Pyridin-3-yl)-16α, 17α-epoxyandrost-5-en-3β-yl acetate
Kavitapu, DasameswaraRao, et al. “New Stability Indicating RP-HPLC Method for the Determination of Abiraterone Acetate, Its Related Substances and Degradation Products in Bulk and Dosage Form.” Materials Today: Proceedings, vol. 34, 2021, pp. 469–78, https://doi.org/10.1016/j.matpr.2020.02.665. ?Mach, Samuel, et al. “Epoxidation Is the Preferred Pathway of First-Stage Metabolism of Abiraterone Acetate in Brown Bullhead (Ameiurus Nebulosus).” Environmental Science and Pollution Research, vol. 26