1449510-64-8: Apixaban Inhouse Impurity E

Apixaban Inhouse Impurity E (CAS No: 1449510-64-8) or 6-(4-(5-Chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide, is a selective factor Xa inhibitor by Inhibition of factor Xa leads to decreased conversion of factor II (prothrombin) to IIa, resulting in decreased thrombin generation used in help prevent strokes or blood clots.

Additional information

Catalogue No.

VE008156

CAS No.

1449510-64-8

Molecular Formula

C25H26ClN5O4

Molecular Weight

495.96 g/mol

IUPAC Name

6-(4-(5-Chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4, 5, 6, 7-tetrahydro-1H-pyrazolo[3, 4-c]pyridine-3-carboxamide

Synonyms

Apixaban Impurity 19

References

Budovich, Aliaksandr, et al. “Role of Apixaban (Eliquis) in the Treatment and Prevention of Thromboembolic Disease.” Pharmacy and Therapeutics, vol. 38, no. 4, 1 Apr. 2013, pp. 206–231, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684191/#b5-ptj3804206.

Status

In-stock