Bicalutamide JP Related substance O
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339530-91-5Bicalutamide JP Related substance O

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Catalogue No.:VE008591
CAS No.:339530-91-5
Mol. Formula:C10H11FO3S
Mol. Weight:230.26 g/mol

Additional information on CAS 339530-91-5

Parent drug

Bicalutamide

IUPAC Name

3-((4-fluorophenyl)thio)-2-hydroxy-2-methylpropanoic acid

Synonyms

N/A

Description

Bicalutamide JP Related substance O (CAS No. 339530-91-5) is an impurity present in Bicalutamide, Bicalutamide blocks the action of androgens of adrenal and testicular origin which stimulate the growth of normal and malignant prostatic tissue, Prostate cancer is mostly androgen-dependent and can be treated with surgical or chemical castration. which is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer.

References

Chen, K.-C., Chen, C.-R., Chen, C.-Y., Tzou, K.-Y., Peng, C.-C., & Peng, R. Y. (2020). Bicalutamide Elicits Renal Damage by Causing Mitochondrial Dysfunction via ROS Damage and Upregulation of HIF-1. International Journal of Molecular Sciences, 21(9), 3400. https://doi.org/10.3390/ijms21093400 ‌ ‌

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