90357-51-0: Bicalutamide Oxirane Impurity
It is an associate impurity Bicalutamide. Bicalutamide is used together with a luteinizing hormone-releasing hormone (LHRH) analog (eg, goserelin or leuprolide) to treat stage D2 metastatic prostate cancer (cancer that has spread) in men. Bicalutamide belongs to the group of medicines called antiandrogens. It works by blocking the effects of testosterone (a male hormone).
Additional information on CAS 90357-51-0
“Sci-Hub, Structural Basis for Antagonism and Resistance of Bicalutamide in Prostate Cancer, 10.1073/Pnas.0500381102.” Hkvisa.net, 2022, sci-hub.hkvisa.net/10.1073/pnas.0500381102.
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