1257099-43-6: Bosentan Impurity 3

Bosentan Impurity 3 (CAS No: 1257099-43-6) or 4-(tert-butyl)-N-(6-(2-(2-hydroxyethoxy)ethoxy)-5-(2-methoxyphenoxy)-[2,2′-bipyrimidin]-4-yl)benzenesulfonamide is associate impurity of Bosentan. Bosentan is employed to treat high blood pressure in the lungs (pulmonary arterial hypertension). This condition is thought to be caused by increased levels of a certain natural substance (endothelin-1). This medication blocks the results of endothelin-1, which helps lower blood pressure in the lungs, slow.

Additional information

Catalogue No.

VE007408

CAS No.

1257099-43-6

Molecular Formula

C29H33N5O7S

Molecular Weight

595.67 g/mol

IUPAC Name

4-(tert-butyl)-N-(6-(2-(2-hydroxyethoxy)ethoxy)-5-(2-methoxyphenoxy)-[2, 2'-bipyrimidin]-4-yl)benzenesulfonamide

References

“Sci-Hub, Clinical Pharmacology of Bosentan, a Dual Endothelin Receptor Antagonist, 10.2165/00003088-200443150-00003.” Hkvisa.net, 2022, sci-hub.hkvisa.net/10.2165/00003088-200443150-00003.

Status

In-stock