1257099-44-7: Bosentan Impurity 4
Bosentan Impurity 4 (CAS No: 1257099-44-7) or 4-(tert-butyl)-N-(5-(2-methoxyphenoxy)-6-(vinyloxy)-[2,2′-bipyrimidin]-4-yl)benzenesulfonamide is associate impurity of Bosentan. Bosentan is employed to treat pulmonary arterial hypertension (PAH, high blood pressure in the vessels that carry blood to the lungs) in adults and children 3 years of age and older. Bosentan could improve the power to exercise and slow the worsening of symptoms in patients with PAH.
“Sci-Hub, Bosentan Therapy for Pulmonary Arterial Hypertension, 10.1056/NEJMoa012212.” Hkvisa.net, 2022, sci-hub.hkvisa.net/10.1056/NEJMoa012212.