253688-61-8: Bosentan O-Desmethyl Impurity

Bosentan O-Desmethyl Impurity (CAS No: 253688-61-8) or 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2’-bipyrimidin]-4-yl]benzenesulfonamide is the associate impurity of Bosentan. Bosentan is an associate endothelin receptor antagonist utilized in the therapy of pulmonary arterial hypertension (PAH).

Additional information

Catalogue No.

VE007404

CAS No.

253688-61-8

Molecular Formula

C26H27N5O6S

Molecular Weight

537.59 g/mol

IUPAC Name

4-(1, 1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2, 2’-bipyrimidin]-4-yl]benzenesulfonamide

References

Gabbay, Eli, et al. “Review of Bosentan in the Management of Pulmonary Arterial Hypertension.” Vascular Health and Risk Management, vol. 3, no. 6, Dove Medical Press, 2007, pp. 887–900,  www.ncbi.nlm.nih.gov/pmc/articles/PMC2350123/.

Status

In-stock