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651-48-9Dehydroepiandrosterone Sulfate Sodium Salt

● Under Development

Catalogue No.:	VL830044
CAS No.:	651-48-9
Mol. Formula:	C19H27O5S. Na
Mol. Weight:	390.47 g/mol

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Additional information on CAS 651-48-9

Parent drug

Abiraterone

IUPAC Name

sodium (3S, 8R, 9S, 10R, 13S, 14S)-10, 13-dimethyl-17-oxo-2, 3, 4, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl sulfate

Pharmacopoeial Synonyms

N/A

Other Synonyms

3-O-Sulfodehydroepiandrosterone;17-Ketoandrost-5-en-3beta-yl sulfate;17-oxoandrost-5-en-3beta-yl hydrogen sulfate

Smiles

O=S(O[C@H](CC1=CC[C@@]2([H])[C@]3([H])CC4)CC[C@]1(C)[C@@]2([H])CC[C@]3(C)C4=O)([O-])=O.[Na+]

InChI

InChI=1S/C19H28O5S.Na/c1-18-9-7-13(24-25(21,22)23)11-12(18)3-4-14-15-5-6-17(20)19(15,2)10-8-16(14)18;/h3,13-16H,4-11H2,1-2H3,(H,21,22,23);/q;+1/p-1/t13-,14-,15-,16-,18-,19-;/m0./s1

Description

Dehydroepiandrosterone Sulfate Sodium Salt is a meticulously characterized reference material that complies with rigorous regulatory requirements, including those defined by USP, EMA, JP, and BP. This product plays a crucial role in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial manufacturing of Abiraterone. It is further supported by a detailed Structure Elucidation Report (SER), ensuring high accuracy and reliability across a broad range of analytical applications. Dehydroepiandrosterone Sulfate Sodium Salt (CAS No: 651-48-9) is a metabolite of Dehydroepiandrosterone sulfate that is secreted primarily by the adrenal gland. It is present in human plasma at a concentration higher than any other steroid hormone.

References

HANING, RAY V., et al. â€œMetabolic Clearance Rate (MCR) of Dehydroepiandrosterone Sulfate (DS), Its Metabolism to Dehydroepiandrosterone, Androstenedione, Testosterone, and Dihydrotestosterone, and the Effect of Increased Plasma DS Concentration on DS MCR in Normal Women *.â€Â The Journal of Clinical Endocrinology & Metabolism, vol. 69, no. 5, Nov. 1989, pp. 1047â€“52, https://doi.org/10.1210/jcem-69-5-1047.