2073864-81-8: Elagolix Impurity 2

Status: Under Development

It is an impurity present in Elagolix, Elagolix is a gonadotropin-releasing hormone receptor antagonist that inhibits endogenous GnRH, By administration of elagolix shows results in dose-dependent suppression of luteinizing hormone and follicle-stimulating hormone, which leads to decreased blood concentrations of the ovarian sex hormones, estradiol, and progesterone, which is used to treat moderate to severe pain in endometriosis.

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Additional information on CAS 2073864-81-8

Catalogue No. VE006362
CAS No. 2073864-81-8
Molecular Formula C31H28F5N3O3
Molecular Weight 585.6
Parent drug Elagolix
IUPAC Name (R)-5-(2-fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methyl-3-(2-phenyl-2-(propan-2-ylideneamino)ethyl)pyrimidine-2, 4(1H, 3H)-dione
Synonyms N/A
References Archer, D. F., Soliman, A. M., Agarwal, S. K., & Taylor, H. S. (2020). Elagolix in the treatment of endometriosis: impact beyond pain symptoms. Therapeutic Advances in Reproductive Health, 14, 263349412096451. https://doi.org/10.1177/2633494120964517 ‌Lamb, Yvette N. “Elagolix: First Global Approval.” Drugs, vol. 78, no. 14, Sept. 2018, pp. 1501–8, https://doi.org/10.1007/s40265-018-0977-4. ‌
Status Under Development

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