Ezetimibe SRS Impurity (CAS No: 1593543-00-0) is a process-related impurity. Ezetimibe is a potent cholesterol absorption inhibitor. It strongly blocks the absorption of biliary and dietary cholesterol from the small intestine. It is evaluated for the treatment of primary hypercholesterolemia, homozygous sitosterolemia, homozygous familial hypercholesterolemia (HoFH), and mixed hyperlipidemia.
References
Filip, Katarzyna, et al. Physicochemical Characterization of Ezetimibe and Its Impurities.†Journal of Molecular Structure, vol. 991, no. 1-3, Apr. 2011, pp. 162–70, https://doi.org/10.1016/j.molstruc.2011.02.020.
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