87625-92-1: Nicardipine Cyclohexenone Impurity

Nicardipine Cyclohexenone Impurity (CAS No: 87625-92-1) is an impurity present in nicardipine which in common with other calcium antagonists, inhibits the slow inward current of calcium in normal cardiac tissues, also it has either significantly shortened or had no effect on sinus nodal recovery time.

Additional information

Catalogue No.

VE007875

CAS No.

87625-92-1

Molecular Formula

C15H15NO5

Molecular Weight

289.28 g/mol

IUPAC Name

Methyl 2-Methyl-6-(3-nitrophenyl)-4-oxo-2-cyclohexene-1-carboxylate

References

“IDENTIFICATION and CHARACTERIZATION of a NOVEL POTENTIAL DEGRADANT and DEVELOPMENT and VALIDATION of STABILITY-INDICATING RP-LC METHOD for NICARDIPINE IMPURITIES in INJECTABLE DOSAGE FORM.” Journal of Liquid Chromatography & Related Technologies, 2013, http://www.tandfonline.com/doi/abs/10.1080/10826076.2012.717056.?Sorkin, Eugene M., and Stephen P. Clissold. “Nicardipine.” Drugs, vol. 33, no. 4, Apr. 1987, pp. 296–345, https://doi.org/10.2165/00003495-198733040-00002.?

Status

In-stock