Nilotinib Impurity 1

Nilotinib Impurity 1 is an impurity present in Nilotinib which is a tyrosine kinase inhibitor approved for the treatment of chronic myelogenous leukemia, is used to treat chronic myeloid leukemia (CML) in people who have tested positive for the Philadelphia chromosome.

Additional information

Catalogue No.

VE006045

CAS No.

N/A

Molecular Formula

C28H21ClF3N7O

Molecular Weight

563.96 g/mol

IUPAC Name

3-(5-chloro-4-(pyridin-3-yl)pyrimidin-2-ylamino)-4-methyl-N-(3-(4- methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide

References

Gopireddy, Ramana Reddy, and Arthanareeswari Maruthapillai. “A Stability Indicating Method Development and Validation for Separation of Process Related Impurities and Characterization of Unknown Impurities of Tyrosine Kinase Inhibitor Nilotinib by RP-HPLC, NMR Spectroscopy and ESI-MS.” Materials Today: Proceedings, vol. 40, 2021, pp. S127–38, https://doi.org/10.1016/j.matpr.2020.03.837.? Kondra, S. B., et al. “A

Status

In-stock