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2484719-17-5O-Chlorobutylabiraterone

● Under Development

Catalogue No.:	VL830019
CAS No.:	2484719-17-5
Mol. Formula:	C28H38ClNO
Mol. Weight:	440.07 g/mol

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Additional information on CAS 2484719-17-5

Parent drug

Abiraterone

IUPAC Name

3Î²-(4-Chlorobutoxyl)-17-(Pyridin-3-yl)androsta-5, 16-diene

Pharmacopoeial Synonyms

N/A

Other Synonyms

Chlorobutoxy Abiraterone;Pyridine, 3-(3-(4-chlorobutoxy)androsta-5,16-dien-17-yl)

Smiles

C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4C5=CN=CC=C5)C)OCCCCCl

InChI

InChI=1S/C28H38ClNO/c1-27-13-11-22(31-17-4-3-15-29)18-21(27)7-8-23-25-10-9-24(20-6-5-16-30-19-20)28(25,2)14-12-26(23)27/h5-7,9,16,19,22-23,25-26H,3-4,8,10-15,17-18H2,1-2H3/t22-,23-,25-,26-,27-,28+/m0/s1

Description

O-Chlorobutylabiraterone is a meticulously characterized reference material that complies with rigorous regulatory requirements, including those defined by USP, EMA, JP, and BP. This product plays a crucial role in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial manufacturing of Abiraterone. It is further supported by a detailed Structure Elucidation Report (SER), ensuring high accuracy and reliability across a broad range of analytical applications. O-Chlorobutylabiraterone (CAS NO-2484719-17-5) is a steroidal compound with antiandrogen activity. Abiraterone is used to treat metastatic, castration-resistant prostate cancer mainly in patients who have undergone chemotherapy. Abiraterone acetate is a prodrug of abiraterone that blocks

References

Works Cited de Bono, Johann S., et al. â€œAbiraterone and Increased Survival in Metastatic Prostate Cancer.â€ New England Journal of Medicine, vol. 364, no. 21, 26 May 2011, pp. 1995â€“2005, 10.1056/nejmoa1014618.