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2147733-69-3Olaparib Impurity 43

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Catalogue No.:	VE0028110
CAS No.:	2147733-69-3
Mol. Formula:	C22H14FN5O2
Mol. Weight:	399.38 g/mol

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Additional information on CAS 2147733-69-3

Parent drug

Olaparib

IUPAC Name

4-(3-(1H-benzo[d][1,2,3]triazole-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one

Pharmacopeial Synonyms

N/A

Synonyms

N/A

Smiles

O=C1C2=C(C=CC=C2)C(CC3=CC=C(C(C(N4N=NC5=CC=CC=C54)=O)=C3)F)=NN1

InChI

InChI=1S/C22H14FN5O2/c23-17-10-9-13(12-19-14-5-1-2-6-15(14)21(29)26-24-19)11-16(17)22(30)28-20-8-4-3-7-18(20)25-27-28/h1-11H,12H2,(H,26,29)

Description

Olaparib Impurity 43 (CAS 2147733-69-3) is a process-related impurity relevant to API quality control and impurity profiling for Olaparib production. It is monitored as part of specification setting and stability studies because trace levels can affect batch release and regulatory acceptance. Analytical characterization typically focuses on chromatographic behavior and mass spectral confirmation to support identification and quantification, and structural elucidation is achieved through orthogonal techniques when needed. Suppliers provide impurity reference material and documentation to support method validation, limit setting and root cause investigations, enabling robust control strategies during synthesis and purification.