Also known as Varenicline DP-I impurity or Varenicline Oxidative Impurity (HCl salt), it is an impurity of Varenicline, varenicline competitively inhibits nicotine binding to a4v2 nAChRs, which prevent nicotine-induced dopaminergic activation.
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![1-((1R,5S)-6-amino-8-nitro-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one](https://veeprho.com/wp-content/uploads/2022/11/1-1R-5S-6-amino-8-nitro-1-2-4-5-tetrahydro-3H-1-5-methanobenzo-d-azepin-3-yl-2-2-2-trifluoroethan-1-one.png "1-((1R,5S)-6-amino-8-nitro-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one")