1-[(4-메틸퀴나졸린-2-일)메틸]-3-메틸-7-(2-부틴-1-일)-8-브로모잔틴, CAS 853029-57-9는 분자식 C20H17BrN6O2, 분자량 453.29 g/mol의 명확히 규정된 합성 잔틴계 공정 불순물이다. 구조적으로는 브로민화 잔틴 핵, 4-메틸퀴나졸린 치환기, 그리고 프로파르길 유래 측쇄를 포함하여, 후기 알킬화 또는 헤테로아릴 결합 단계에서 생성되거나 유사 중간체의 불완전 분리로 발생할 가능성을 시사한다. 미량 정량에는 일반적으로 LC-MS/MS 또는 고해상도 LC-MS가 요구되며, 역상 HPLC 분리와 필요 시 NMR, LC-UV를 병행하여 불순물 특성을 규명한다. 규제 평가는 구조적 경고와 ICH M7 맥락을 반영해야 한다.
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![1-[(4-Methylquinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-bromoxanthine](https://veeprho.com/wp-content/uploads/2026/03/1-4-Methylquinazolin-2-ylmethyl-3-methyl-7-2-butyn-1-yl-8-bromoxanthine-853029-57-9-VE007277-1efb-sqr.png "1-[(4-Methylquinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-bromoxanthine")
