1382475-35-5Abiraterone Mesylate
● Under Development
| 카탈로그 번호: | VL830040 |
|---|---|
| CAS 번호: | 1382475-35-5 |
| 분자식: | C25H33NO3S |
| 분자량: | 427.6 g/mol |
에 대한 추가 정보 CAS 1382475-35-5
모약물
AbirateroneIUPAC명
(3S, 10R, 13S)-10, 13-dimethyl-17-(pyridin-3-yl)-2, 3, 4, 7, 8, 9, 10, 11, 12, 13, 14, 15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl methanesulfonate약전 동의어
N/AOther Synonyms
Abiraterone Acetate P-Toluene Sulfonyl EsterSMILES
CS(=O)(O[C@H]1CC[C@]2(C)C3CC[C@]4(C)C(C5=CC=CN=C5)=CCC4C3CC=C2C1)=OInChI
InChI=1S/C25H33NO3S/c1-24-12-10-19(29-30(3,27)28)15-18(24)6-7-20-22-9-8-21(17-5-4-14-26-16-17)25(22,2)13-11-23(20)24/h4-6,8,14,16,19-20,22-23H,7,9-13,15H2,1-3H3/t19-,20?,22?,23?,24-,25+/m0/s1설명
Abiraterone Mesylate is a meticulously characterized reference material that complies with rigorous regulatory requirements, including those defined by USP, EMA, JP, and BP. This product plays a crucial role in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial manufacturing of Abiraterone. It is further supported by a detailed Structure Elucidation Report (SER), ensuring high accuracy and reliability across a broad range of analytical applications. Abiraterone Mesylate or (3S,10R,13S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl methanesulfonate, it is a active inhibitor of the steroidal enzyme CYP17A1 and is used in the treatment of prostate cancer.
References
Thakur, Abhimanyu, et al. “Abiraterone Acetate in the Treatment of Prostate Cancer.†Biomedicine & Pharmacotherapy, vol. 101, May 2018, pp. 211–218, 10.1016/j.biopha.2018.02.067.견적 요청
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