Albuterol Related Compound F, 즉 salbutamol ethyl ether hydrochloride는 β2-아드레날린 작용제 관련 공정 불순물로서 분자식 C15H26ClNO3, 분자량 303.82 g/mol을 갖는다. 이 물질은 salbutamol 골격의 페놀성 하이드록실기가 O-에틸화된 구조로, 합성 단계에서 생성되는 알킬 에터 부산물 또는 의도치 않은 에틸화 불순물로 해석된다. 염산염 형태는 극성 및 이온화 거동을 변화시키므로, 극미량 정량에는 일반적으로 LC-MS/MS 또는 고분해능 LC-MS가 요구되며, 불순물 프로파일링에서는 LC-UV와 NMR에 의한 정합성 확인이 병행된다. 규제적 관점에서 주된 의미는 β2-작용제 계열의 구조적 불순물 규명에 있다.
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