Bupropion Des-Tbutylamino Impurity는 3′-chloropropiophenone 또는 m-chloropropiophenone으로도 불리는 방향족 알킬 케톤으로, 분자식은 C9H9ClO, 분자량은 168.62 g/mol이며 CAS 34841-35-5이다. 이 물질은 반응성이 큰 헤테로원자 함유 분해산이라기보다 Friedel-Crafts 아실화 또는 유사한 방향족 케톤 합성에서 기원하는 공정 관련 불순물 또는 합성 전구체로 해석된다. 불순물 동정과 정량에는 GC-MS, LC-MS/MS가 통상 필요하며, 구조 확증을 위해 고분해능 질량분석 및 NMR이 추가로 사용된다.
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