Empagliflozin Impurity 11, 즉 deschloro empagliflozin(CAS 2452301-27-6)은 SGLT2 억제제의 구조 유사체로서 방향족 염소 치환기가 결여된 화합물이다. 분자식은 C23H28O7이며 분자량은 416.5 g/mol이다. 이러한 불순물은 산화적 분해보다는 합성 중 할로겐화 제어 불완전 또는 전구체 잔류 이행과 더 밀접하게 연관된다. 모화합물과의 크로마토그래피 거동이 유사하므로, 식별과 정량에는 LC-MS/MS, 고해상도 LC-MS 및 NMR이 필요하다. 니트로사민 계열은 아니지만, ICH 기반 불순물 평가에서 공정 유래 불순물로서 규제적으로 중요하다.
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