Lercanidipine Inhouse Impurity D, 즉 dehydro lercanidipine, CAS 887769-34-8은 디하이드로피리딘계 칼슘 채널 차단제인 레르카니디핀에서 유래한 산화성 공정 또는 분해 관련 유사체이다. 분자식 C36H39N3O6와 분자량 609.71 g/mol은 모체 골격의 형식적 탈수소화와 일치하며, 이에 따라 헤테로고리의 산화 상태와 크로마토그래피 거동이 변한다. 이러한 불순물은 일반적으로 안정성 지시 HPLC와 다이오드 어레이 검출로 분리되고, LC-MS/MS로 확인되며, 원소 조성 부여에는 HRMS가 유용하다. ICH Q3A 및 Q3B 관점에서 불순물 프로파일링에 의미가 있다.
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