Metoprolol EP Impurity J, CAS 163685-37-8,는 베타차단제 메토프로롤과 관련된 구조적으로 규정된 공정 유래 불순물이다. 분자식 C18H31NO5, 분자량 341.44 g/mol이며, 메토프로롤 유사체에 특징적인 2차 아미노알코올 골격을 갖는 하이드록실화 에터 유도체에 해당한다. 그 생성은 일반적으로 합성 경로의 변동, 과산화, 또는 측쇄 조립 중 불완전 전환과 연관되며, 전형적인 가수분해 분해산은 아니다. 미량 수준의 동정 및 정량에는 보통 LC-MS/MS, 고해상도 MS, 그리고 LC-UV 또는 NMR의 상보적 확인이 요구된다.
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